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For which patients is Lenvatinib used?

Lenvatinib is used for patients with:

Thyroid cancer: It is indicated for the treatment of locally recurrent or metastatic differentiated thyroid carcinoma that is refractory to radioactive iodine therapy.

Hepatocellular carcinoma (HCC): Lenvatinib is used for patients with unresectable HCC who have not received prior systemic therapy.

Renal cell carcinoma (RCC): It can be used in combination with everolimus for patients with advanced renal cell carcinoma who have received prior anti-angiogenic therapy.

Endometrial carcinoma: Lenvatinib is also indicated in combination with pembrolizumab for patients with advanced endometrial carcinoma who have progressed following prior treatment.Know more about Lenvatinib Price Malaysia

Lenvatinib works as a multi-kinase inhibitor, targeting various receptors involved in tumor growth and angiogenesis. Treatment decisions should always be made in consultation with a healthcare provider based on the individual patient's condition and overall health.

What is the indication for Lenvatinib acetate?

Lenvatinib acetate is indicated for the treatment of:

Differentiated thyroid cancer: For patients with locally recurrent or metastatic disease that is refractory to radioactive iodine therapy.

Hepatocellular carcinoma (HCC): For patients with unresectable HCC who have not received prior systemic therapy.

Renal cell carcinoma (RCC): In combination with everolimus for patients with advanced renal cell carcinoma who have received prior anti-angiogenic therapy.

Endometrial carcinoma: In combination with pembrolizumab for patients with advanced endometrial carcinoma that has progressed following prior treatment.

Lenvatinib acts as a multi-kinase inhibitor, targeting various pathways involved in tumor growth and angiogenesis. Always consult a healthcare provider for specific treatment recommendations based on individual circumstances.

What are the cautions of Lenvatinib?

Lenvatinib has several cautions to consider:

Hypertension: Lenvatinib can cause significant increases in blood pressure, so regular monitoring is essential.

Hepatotoxicity: Liver function tests should be monitored, as lenvatinib can lead to liver enzyme elevations and liver dysfunction.

Thyroid function: Patients may experience hypothyroidism; thyroid function tests should be monitored regularly.

Gastrointestinal perforations: There is a risk of gastrointestinal perforations, which can be serious.

Wound healing: Lenvatinib may impair wound healing, so caution is advised in patients undergoing surgery.

Proteinuria: Patients should be monitored for proteinuria, as it can occur with lenvatinib treatment.

QT interval prolongation: Caution is needed in patients with a history of QT prolongation or those on medications that affect the QT interval.

Pregnancy and breastfeeding: Lenvatinib is contraindicated during pregnancy and breastfeeding due to potential harm to the fetus or infant.

Drug interactions: Lenvatinib can interact with various medications, especially those affecting liver enzymes, necessitating a comprehensive review of the patient’s medications.

Patients should discuss these cautions with their healthcare provider to ensure safe and effective use of lenvima 4mg price.


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