Plasmid DNA is circular, double stranded DNA. It acts as a vector and is used to manipulate genes and transport them into host cells. Plasmids are considered key elements for cell and gene therapies, DNA vaccines, and recombinant protein production. Growing demand for gene and cell therapies and DNA vaccines is driving the need for large-scale, high-quality plasmid DNA for research and clinical applications. Key players in the plasmid DNA manufacturing market offer services for end-to-end development and manufacture of plasmids under cGMP guidelines. Players focus on technologies like closed and automated systems for plasmid production to minimize contamination and increase yield.

The global plasmid DNA manufacturing market is estimated to be valued at US$ 1038.19 Mn in 2024 and is expected to exhibit a CAGR of 4.8% over the forecast period from 2024 to 2031.

Key Takeaways

Key players operating in the plasmid DNA manufacturing market are Cobra Biologics and Pharmaceutical Services (Charles River Laboratories), VGXI, Inc., Aldevron (Danaher), Kaneka Corporation, Nature Technology, PlasmidFactory GmbH & Co. KG, Cell and Gene Therapy Catapult, LakePharma, Inc., MeiraGTx Limited, Eurofins Genomics, Vigene Biosciences, Luminous BioSciences (LBS), LLC, GenScript, GENEWIZ, Creative Biogene, Akron Biotech, Biomay, JAFRAL Ltd., WuXi Biologics, GeneImmune Biotechnology Corp., Lonza, Greenpak Biotech Ltd., Luina Bio (AcuraBio), Ajinomoto Bio-Pharma, Synbio Technologies, Genopis Inc., Altogen Biosystems, Puresyn, Inc., Cepham Life Sciences, Catalent, Inc., Biomiga, Waisman Biomanufacturing.

The growing demand for Plasmid DNA Manufacturing Market Demand from the cell and gene therapy sector is a major driver for the market. Increasing clinical research activities and approvals for cell and gene therapies will require large volumes of high-quality plasmids.

Several market players are partnering or acquiring manufacturers to expand global plasmid DNA production capacity as the market potential increases. They aim to serve the worldwide demand through a geographically expanded network.

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